Benefits of neem for Oral lichen planus patients.

Phase 3

Completed

Conditions: Other specified disorders involving the immune mechanism, not elsewhere classified, Symptomatic Oral Lichen Planus patients coming to the OPD of Oral Medicine and Radiology Department of S.P.D.C. DMIMS Sawangi, Wardha and fulfilling the inclusion criteria. ,

Brief Summary: Lichen planus is a chronic mucocutaneous disease with variable etiologies. As there is no established cure variable treatment modalities are available most of which provide symptomatic relief only to recur later. Neem has been considered wonder drug exhibiting various properties like antiinflammatory, immnomodulating, antifungal etc. hence this study is planned to evaluate the effectiveness of neem in oral lichen planus patients.

Recruitment & Eligibility

Inclusion Criteria

1.Symptomatic Patients with any clinical types and manifestations of OLP and those confirmed histopathologically will be included in the study.
2.Patients who have discontinued previous treatment for OLP for last six months.

Exclusion Criteria

1.Patients younger than 16 years old.
2.Patients with skin lesions.
3.Patients with non symptomatic OLP lesions 4.Patients with lesions showing malignant or dysplasic changes.
5.Patients undergoing any other treatment for oral lichen planus.
Pregnant and nursing woman.
Patients having systemic problems or under any medications for the same.
Patients having habit of chewing tobacco and betelnut or smoking.

Primary Outcome Measures

Name	Time	Method
Burning sensation will be evaluated by visual analog scale.	Burning sensation and \| The severity of lesions on each side will be evaluated on 1st day, 3rd day, 7th day, 2nd week, 3rd week, 4th week, 2nd month, 3rd month.
The severity of lesions on each side will be evaluated by Thongprasom criteria.	Burning sensation and \| The severity of lesions on each side will be evaluated on 1st day, 3rd day, 7th day, 2nd week, 3rd week, 4th week, 2nd month, 3rd month.

Secondary Outcome Measures

Name	Time	Method
Acceptability of neem mouthwash.	Total duration required to decrease the symptoms.

Locations (1): Sharad Pawar Dental College and hospital
🇮🇳
Wardha, MAHARASHTRA, India
Sharad Pawar Dental College and hospital
🇮🇳Wardha, MAHARASHTRA, India
Ashita Kalaskar
Principal investigator
8550928585
kalaskarashita@gmail.com