Validity of Non-invasive Liver Fibrosis Assessment by Ultrasound-based Elastography at the Third Trimester of Pregnancy: a Prospective Study
试验速览
- 阶段
- 不适用
- 状态
- 暂停
- 发起方
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- Difference between the fibrosis score during and after pregnancy
研究概览
简要总结
Non invasive methods are the only available methods to stage liver fibrosis during pregnancy. The safety of elastometry - ultrasound based - is obvious, as medical supervision of pregnancy is based on ultrasonography, both methods using same wavelengths. Therefore, this method is sometimes used in pregnant women with recent diagnosis of chronic viral hepatitis infection, whereas its validity in pregnant women has never been studied. This lack of data justifies our study.
详细描述
One measurement during the third trimester of pregnancy will be compared to a second measurement, 3 months after childbirth.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Pregnant women
- •Followed in Obstetrics Dpt
- •HBV or HCV chronic hepatitis
- •After information and written consent
排除标准
- 未提供
结局指标
主要结局
Difference between the fibrosis score during and after pregnancy
时间窗: 3 to 6 months after delivery
次要结局
未报告次要终点
研究者
Stephane Mouly, MD PhD
Professor Paris VII University, Paris, France
Hopital Lariboisière