Assessment of reversal time characteristics using full dose with two step administration of Neostigmine for antagonizing Atracurium induced moderate block using neuromuscular monitor .A Double blinded randomized control trial
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 88
- 试验地点
- 1
- 主要终点
- administration.
研究概览
简要总结
Assessment of reversal time characteristics using full dose with two step administration
of Neostigmine for antagonizing Atracurium induced moderate block using
neuromuscular monitor –Double blinded randomized control trial
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patient belonging to ASA 1 and 2 2.Patient posted for surgeries under general anaesthesia in PIMS 3.BMI -18 to 35 kg/m
- •Surgeries lasting for less than 2 hours.
排除标准
- •)Known allergy to anaesthetic drugs 2)Neuromuscular disease 3)Renal disorders ( serum creatinine > 1.8mg/dl) 4)Liver disorders ( liver function tests > 50% of normal value ) 5) Surgical position that prevent access to neuromuscular monitoring.
结局指标
主要结局
administration.
时间窗: Assessed intraoperatively and postoperatively 1hour(surgeries not more than approximately 2hours ).
To measure the effect of two step administration of neostigime after emergence of
时间窗: Assessed intraoperatively and postoperatively 1hour(surgeries not more than approximately 2hours ).
TOFc of 3 in reducing the reversal time of atracurium induced moderate block in patient
时间窗: Assessed intraoperatively and postoperatively 1hour(surgeries not more than approximately 2hours ).
undergoing general anaesthesia using inhalational anaesthesia as compared to full dose
时间窗: Assessed intraoperatively and postoperatively 1hour(surgeries not more than approximately 2hours ).
次要结局
- 1. To note the incidence of residual neuromuscular blockade postoperatively(2.To document the side effects of neostigmine)
研究者
Mahalakshmi M
Pondicherry Institute of Medical sciences