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SOLO-Symbicort® in the Treatment of Persistent Asthma in Adolescents & Adults

Phase 3
Completed
Conditions
Asthma
Registration Number
NCT00238784
Lead Sponsor
AstraZeneca
Brief Summary

The purpose of this study is to compare Symbicort Single Inhaler treatment with the Best Conventional Practice in patients with persistent asthma

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
1300
Inclusion Criteria
  • Diagnosis of asthma < 3 months
  • Prescribed daily use of glucocorticosteroids for at least 3 months prior to Visit 1
Exclusion Criteria
  • Smoking history > 10 pack-years
  • Asthma exacerbation requiring change in asthma treatment during the last 14 days prior to inclusion
  • Any significant disease or disorder that my jeopardize the safety of the patient.

Additional inclusion and exclusion criteria will be evaluated by the investigator.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Time to first severe asthma exacerbation
Secondary Outcome Measures
NameTimeMethod
Patient reported Outcomes
All variables assessed over the 6 months treatment period
Number of asthma exacerbations
Health care resource use
Mean use of as-needed medication
Safety: Adverse Events, Serious Adverse Events and discontinuations due to Adverse Events
Induced sputum will be sampled from a subset of patients
Prescribed asthma medication

Trial Locations

Locations (1)

Research Site

🇨🇦

Brampton, Ontario, Canada

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