Locally Advanced Colorectal Cancer and Local Recurrences in Västra Götaland

Recruiting

• Conditions: Colorectal Neoplasms
• Interventions: Procedure: Surgery or treatment for local recurrence; Procedure: Surgery for advanced colorectal cancer

• Registration Number: NCT04406974
• Lead Sponsor: Sahlgrenska University Hospital, Sweden

Brief Summary

The aim of this study is to review the treatment strategies of locally advanced colorectal cancer and locally recurrent rectal cancer in Västra Götaland during 1995-2016. The aim is to evaluate time trends and outcome both related to morbidity and cancer specific survival, we will also evaluate the results after advanced reconstruction. The study will identify the population using the Swedish ColoRectal Cancer Registry and then the individual patient charts will be reviewed. The data will be collected in a clinical record form covering demography (age, sex, co-morbidity, BMI and diagnoses) as well as treatments strategy, surgical procedures, re-operations, complications, readmissions, hospital stay, stoma formation etc.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-01-01
• Study First Submitted: 2020-05-24
• Study First Submitted QC: 2020-05-24
• Study First Posted: 2020-05-29
• Primary Completion: 2022-12-01
• Status Verified: 2023-12
• Last Update Submitted: 2023-12-07
• Last Update Posted: 2023-12-08
• Study Completion: 2024-12-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 4000

Inclusion Criteria

• Locally advanced rectal cancer
• Local recurrence for colorectal cancer
• Curative treatment for colorectal cancer

Exclusion Criteria

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients with advanced colorectal cancer	Surgery or treatment for local recurrence	-
Patients with local recurrence	Surgery for advanced colorectal cancer	-
Patients with advanced colorectal cancer	Surgery for advanced colorectal cancer	-
Patients with local recurrence	Surgery or treatment for local recurrence	-

Primary Outcome Measures

Name	Time	Method
Patient experiences after local recurrence	3 years postopeartively after local recurrence	Indepth interviews with patients with local recurrence
Complications after urinary reconstruction surgery for locally advanced cancer	90 days
Survival after local recurrence	3 years
Risk factors for local recurrence	Preoperative data, about 1 month prior surgery

Trial Locations

Locations (1)

Dept. of Surgery, Sahlgrenska University Hospital/Ostra; 🇸🇪 Gothenburg, Sweden