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临床试验/NCT02652325
NCT02652325Unknown不适用

Comparison of Effectiveness of Povidone-iodine Versus Saline Versus 3M Skin and Nasal Antiseptic 5% Povidone-Iodine USP Swabs for Decolonizing Intranasal MSSA/MRSA

Rothman Institute Orthopaedics0 个研究点开始时间: 2016年1月11日最近更新:
适应症
干预措施
相关药物

试验速览

阶段
不适用
主要终点
MSSA/MRSA colonization as tested by PCR

研究概览

简要总结

To determine if routinely available 10% povidone-iodine swabs are more effective than saline and 3M Skin and Nasal Antiseptic 5% Povidone-Iodine USP for decolonizing MRSA.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Screening
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • All potential total hip and total knee arthroplasty candidates
  • All femoroacetabular osteoplasty patients
  • All pelvic acetabular osteotomy patients
  • All core decompression patients

排除标准

  • Any trauma patients
  • Any tumor patients
  • Any patient with periprosthetic joint infection
  • Any patient with surgical site infection
  • Any patient with known MRSA infection
  • Any patients allergic to povidone-iodine
  • Patients with thyroid disease

研究组 & 干预措施

povidone-iodine

Active Comparator

干预措施: Povidone-Iodine (Drug)

3M Skin and Nasal Antiseptic 5% Povidone-Iodine USP swabs

Active Comparator

干预措施: 5% Povidone-Iodine USP swabs (Drug)

Saline

Placebo Comparator

干预措施: Saline (Drug)

结局指标

主要结局

MSSA/MRSA colonization as tested by PCR

时间窗: 24 hours

Subjects will undergo a swab of their nares to undergo PCR analysis to determine if they are effectively decolonized four hours after initial treatment

MSSA/MRSA colonization in the nares

时间窗: 4 hours

Subjects will undergo a swab of their nares to undergo PCR analysis to determine if they are effectively decolonized four hours after initial treatment

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

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