Non-invasive techniques to improve sleep disturbance induced cognitive impairments

Not yet recruiting

Conditions: Sleep disturbance

Registration Number: CTRI/2019/05/019154

Lead Sponsor: Department of Science and Technology

Brief Summary: Problems related to sleep are very common in modern society. Consequences of sleep problems can be many out of which decrements incognitive performance is amongst the top ranked ill effect. Physiologically, lack of slow wave activity (SWA) occurring duringslow-wave sleep (SWS) is by far the most argued reason for cognitivedecline associated with sleep problems. Moreover, SWA and its coupling with othersleep features, reorganizes cortical circuitry, supporting cognition. SWA enhancement techniques range from behavioural interventions (such asvarious forms of exercises), which have high feasibility but low specificity,to laboratory based techniques (such as brain wave stimulation), which havehigh specificity but are less feasible for widespread use. Here, we propose to examine the effects of two SWA enhancement techniques on sleep and cognitive functions. Therefore, the present study is a randomised, single blinded, multiple arm comparative trial to ascertain the effects of non invasive, non pharmacological SWA enhancement techniques, i.e., Aerobic exercise and Brain wave entrainment on sleep and cognition in collegiate students. Apart from sleep and cognition, this study also intends to investigate the effect of SWA enhancement techniques on stress, anxiety, quality of life, well-being and biomarkers of sleep and cognitive function in sleep disturbed collegiate students. This study is to be conducted in Jamia Millia Islamia. The participants will be recruited from the University campus. If came out with positive results, this study protocol has the potential to be used for improving sleep as well as cognitive functions inuniversity students.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 30

Inclusion Criteria

Subjects volunteering to participate in the study A score >5 on Kuppuswamy socio-economic status scale Physician approval for participation in study program Subjects having basic understanding of English language.

Exclusion Criteria

History of any neurological, psychological and psychiatric disorders History or evidence of cardiovascular disease (history of angina, shortness of breath, uncontrolled hypertension) Alcoholism and other drug abuse/ smoking Use of centrally active medications Use of sleep medications Receiving any physical therapy intervention or engaged in any regular physical activity program for last 6 months.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Quality and quantity of sleep, Cognitive functions	Baseline, 4th week, 8th week

Secondary Outcome Measures

Name	Time	Method
Subjective stress, Anxiety, Quality of life, Well being, Biomarkers of sleep and cognition	Baseline, 4th week, 8th week

Trial Locations

Locations (1): Jamia Millia Islamia
🇮🇳
West, DELHI, India
Jamia Millia Islamia
🇮🇳West, DELHI, India
Prof Mohammed Ejaz Hussain
Principal investigator
9899339816
ehusain@jmi.ac.in