a pilot study to investigate the hepcidin levels in patients with rheumatoid arthtitis treated with IL-6R blockade
Completed
- Conditions
- anemia of chronic disease1000208610013361
- Registration Number
- NL-OMON33066
- Lead Sponsor
- HagaZiekenhuis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
Moderate to severe active RA
Age > 18
treatment with anti-IL-6R
Exclusion Criteria
Major surgery within 8 weeks prior to screening
Prior history of inflammatory (joint) disease other than RA
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>To determine the hepcidin levels before, 2, 4, 8 and 24 hours after the<br /><br>administration of anti-IL-6R in patients with RA.</p><br>
- Secondary Outcome Measures
Name Time Method <p>To determine the levels of Iron, transferrin , (calculation of transferrin<br /><br>saturation), ferritin, Hb, CRP and IL-6 before, 2, 4,8 and 24 hours after<br /><br>anti-IL-6R administration in patients with RA.</p><br>