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临床试验/NCT05334355
NCT05334355已完成不适用

Impact of a Family History of Hypertension and Physical Activity on Left Ventricular Mass

Montclair State University0 个研究点目标入组 74 人开始时间: 2016年4月19日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
74
主要终点
Left Ventricular Mass

研究概览

简要总结

This is a retrospective analysis of data collected within two previous studies. The data has been combined and used to investigate the impact of having a family history of hypertension on left ventricular muscle mass with and without controlling for moderate and vigorous intensity physical activity frequency per week. The hypothesis was that in a sample of mostly active participants, no differences in left ventricular mass between family history of hypertension groups would be observed, but the positive family history of hypertension group would have elevated left ventricular mass compared to the negative family history of hypertension group following statistical control of activity frequency.

详细描述

A positive family history of hypertension (FHH) (+FHH) is associated with elevated left ventricular mass (LVM). Regular physical activity (PA) may eliminate differences in LVM between +FHH and negative family history of hypertension (-FHH) adults. PURPOSE: To determine if a +FHH is associated with a greater LVM compared to a -FHH group within a sample of young, mostly active healthy adults with and without statistically controlling for PA. METHODS: Healthy young (18-32yrs) participants self-reported FHH status and habitual moderate and vigorous PA frequency. Participants then underwent an echocardiogram.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 32 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Generally healthy

排除标准

  • Known hypertension, cardiovascular disease, current pregnancy, current infectious disease, diabetes mellitus, kidney disease, a history of cancer, pulmonary disease, history of a stroke, obesity (for most people this means a body mass index greater than 30), or any life threatening chronic conditions

结局指标

主要结局

Left Ventricular Mass

时间窗: Day 2

Muscle mass in grams of the left ventricle of the heart as estimated by ultrasound.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Evan Matthews

Associate Professor

Montclair State University

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