Injection of 5-fluorouracil in treatment of keloids
Not Applicable
Not yet recruiting
- Conditions
- Health Condition 1: L918- Other hypertrophic disorders of the skin
- Registration Number
- CTRI/2020/03/024219
- Lead Sponsor
- ok Nayak Hospital and associated MAMC
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All patients between 18-60 years, having keloid scars with maximum scar size of 20 cm2.
If one patient has multiple scars, no more than two scar sites will be included in the study.
Exclusion Criteria
-Pregnancy and lactation
-Patients with co-morbidities like diabetes, hypertension, coronary artery disease, chronic liver disease.
-Any patient with history of treatment with intralesional steroid injection in previous six months for the same site.
-Infected keloids
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical scar assessment based on Vancouver Scar Scale (VSS) that scores the scars on four parameters namely pigmentation, vascularity, pliability and height.Timepoint: At the end of each injection session and till last follow up scheduled at monthly intervals for 2 months.
- Secondary Outcome Measures
Name Time Method Pain assessment as per Visual Analogue Scale (VAS) <br/ ><br> <br/ ><br>Adverse effects such as ulceration, telengectasias, skin atrophy, infection, pigmentary changes, any other. <br/ ><br>Timepoint: At the end of each injection session and till last follow up scheduled at monthly intervals for 2 months.