Manual Therapy Effects on Upper and Lower Esophageal Sphincter Pressures
- Conditions
- Gastroesophageal Reflux DiseaseGlobus Pharyngeus
- Registration Number
- NCT03871426
- Lead Sponsor
- University Hospital, Motol
- Brief Summary
The aim of this study is to test the influence of manual cervical traction and chest stabilization maneuvers on pressures in upper and lower esophageal sphincters.
- Detailed Description
High Resolution Manometry (HRM) will be used to measure pressure changes in upper esophageal sphincter (UES) and lower esophageal sphincter (LES) during manual cervical traction and trunk stabilization maneuvers. 50-55 gastroesophageal reflux disease (GERD) subjects will participate in the study. UES and pressures will first be measured in relaxed supine position then, during manual cervical traction and finally, the subjects will undergo manual positioning of the trunk into neutral position and LES and UES pressures will be measured again.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 54
- Gastroesophageal reflux disease
- Previous gastro- esophageal surgery
- Concomitant other chronic disease that would affect esophageal motility
- Esophageal structural pathology
- Massive hiatus hernia
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pressure in upper and lower esophageal sphincter up to 6 months Pressure in upper and lower esophageal sphincter at rest, during cervical manual traction, and during trunk stabilization maneuver
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Department of Rehabilitation and Sports Medicine, University Hospital Motol, Prague, Czech Republic
🇨🇿Prague, Czechia