NCT06041126
Completed
Not Applicable
The Effect of Disease Severity and Respiratory Functions on Muscle Oxygenation in Stable COPD Patients
Bandırma Onyedi Eylül University1 site in 1 country41 target enrollmentApril 24, 2023
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Chronic Obstructive Pulmonary Disease
- Sponsor
- Bandırma Onyedi Eylül University
- Enrollment
- 41
- Locations
- 1
- Primary Endpoint
- Muscle oxygenation
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
The aim of this study is to examine the peripheral muscle oxygenation of patients with Chronic Obstructive Pulmonary Disease at rest, during submaximal exercise and recovery, and to examine the effects of disease severity and respiratory functions on peripheral muscle oxygenations. In this study, the effect of disease severity and respiratory problems on peripheral muscle metabolism of patients with COPD will be explained.
Investigators
Gulhan Yilmaz Gokmen
Assistant Professor
Bandırma Onyedi Eylül University
Eligibility Criteria
Inclusion Criteria
- •Being diagnosed with COPD (according to GOLD Staging: GOLD 1, GOLD 2, GOLD 3, GOLD 4)
- •Being between the ages of 40-80
- •Body Mass Index \<35
- •Not having an acute exacerbation in the last 3 months
Exclusion Criteria
- •Patients who do not want to participate in the study
- •Arthritis causing weakness in the lower extremity, neurological disease, deep vein thrombosis, peripheral arterial disease, muscle weakness, fracture etc. patients with the condition
- •Common diseases such as malignancy, pulmonary embolism, vasculitis, collagen tissue diseases, interstitial fibrosis, severe pneumonia patients with parenchymal destruction
- •Patients with severe dyspnea and hemodynamic instability who cannot perform the 6 Minute Walk Test
Outcomes
Primary Outcomes
Muscle oxygenation
Time Frame: one day
The muscle oxygen monitor is a lightweight (42 g) and small (dimensions: 61 × 44 × 21
Secondary Outcomes
- COPD Assessment Test (CAT)(one day)
- Six-minute walking test(one day)
- Pulmonary Function Test(one day)
- Maximum Inspiratory Pressure / Maximum Expiratory Pressure Measurement(one day)
- Modified Medical Research Council Dyspnea Scale(one day)
- Charlson Comorbidity Index(one day)
- Quadriceps muscle strength measurement(one day)
Study Sites (1)
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