Efficacy and Safety of Tadalafil in Hemodialysis Patients
- Conditions
- Erectile Dysfunction
- Registration Number
- NCT00334477
- Lead Sponsor
- University of Pernambuco
- Brief Summary
The purpose of this study is to check the safety and efficacy of a pde5 inhibitor, tadalafil, is a special group of patients: Renal chronic patients in hemodialysis treatment.
- Detailed Description
In our country, the number of patients in hemodialysis for the treatment of renal chronic dysfunction is very huge. As we know this group has a greater prevalence of sexual dysfunction than the general population, and among these dysfunctions erectile disfunction(ED) occupies maybe the most important position.
With the advent of the increase aging of the nation´s population and the small number of organ donations, the number of men suffering from ED in hemodialysis surely will be very significant causing a very important problem for our health system.
Up to now there´s little indexed publications supporting the use of tadalafil in this special group of men. Another PDE 5 inhibitor, sildenafil, was used in this patients with success and safety but obviously we need other options with the same efficacy.
We intend this study to give us more background to treat ED in this already unfortunate ones.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Male
- Target Recruitment
- 60
- Men between 18 and 70 years old
- Diagnosticated ED for 6 months at least
- Accept the protocol
- Sign the informed consent
- Renal chronic patients in hemodyalisis
- History of another PDE5 inhibittor use.
- C.C.I. grade III (NYHA)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method IIEF 5
- Secondary Outcome Measures
Name Time Method adverse effects reported
Trial Locations
- Locations (1)
Hospital de Aeronautica de Recife
🇧🇷Recife, Pernambuco, Brazil