MedPath

Fixed-dose combination of losartan and hydrochlorothiazide significantly improves endothelial function in uncontrolled hypertension by low dose amlodipine

Not Applicable
Recruiting
Conditions
The investigation on the effect of medication in patients with uncontrolled hypertension on endothelial function
Registration Number
JPRN-jRCT1091220222
Lead Sponsor
Bonpei Takase
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
50
Inclusion Criteria

uncontrolled hypertension despite use of amlodipine (2.5 mg daily)

Exclusion Criteria

Severe compliocations, malignancy, acute illness

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
endothelial function
Secondary Outcome Measures
NameTimeMethod
blood pressure decrease
© Copyright 2025. All Rights Reserved by MedPath