Comparison of dexmedetomidine, fentanyl, ketamine nebulization as an adjuvant to lignocaine for awake fibreoptic intubation.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 84
- 试验地点
- 1
- 主要终点
- 1.To determine the cough score.
研究概览
简要总结
This study is a randomized, double blind, parallel group, single centre trial comparing the effect of dexmedetomidine(1 mcg/kg), fentanyl( 2 mcg/kg), ketamine( 2mg/kg) in addition to 4 % lignocaine (160mg) nebulization during awake fibreoptic intubation. The primary outcome measures will be the cough score and rate of glottic closure at the time from the starting of intubation till the tube reaches the trachea. The secondary outcomes will be sedation score and to observe for other adverse effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients under the category of ASA I/II(American Society of Anaesthesiologist).
排除标准
- •1.Previous Airway surgery 2.Anticipated difficult airway 3.Nasal Trauma 4.Allergy to Local Anesthetics.
结局指标
主要结局
1.To determine the cough score.
时间窗: the time from the starting of intubation till the tube reaches the trachea (about 30sec)
2.To determine the rate of glottic closure during bronchoscopy and intubation.
时间窗: the time from the starting of intubation till the tube reaches the trachea (about 30sec)
次要结局
- 1.To evaluate sedation score.(2.To observe for any other adverse effects.)