Predictive model for the sensitising capacity of novel nutritional proteins.

• Conditions: allergy; Food hypersensitivity; 10001708

• Registration Number: NL-OMON51765
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

Signed informed consent
18 years of age or older, mentally competent
Patients suspected of a food allergy to peanut, or cow's milk, or hen's egg
Complaints after consuming peanut, or cow's milk, or hen's egg
Positive Skin Prick test with peanut, or cow's milk, or hen's egg

Exclusion Criteria

Patient eats peanut, or cow's milk, or hen's egg, without complaints
Negative skin prick test with peanut, or cow's milk, or hen's egg
Negative DBPCFC with peanut, or cow's milk, or hen's egg
Antihistamines used in the last 72 hours before the skin prick test and/or
DBPCFC
Unable to stop beta-blockers
Use of more than 10 mg prednisone (relative contraindication)

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>IL-13 (biomarker) production by human donor blood cells in the new in vitro<br /><br>assays.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>not applicable</p><br>