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Clinical Trials/NCT01569165
NCT01569165CompletedNot Applicable

Effect of Water Rinsing After APF Application on Dental Plaque Acidogenicity

Mashhad University of Medical Sciences1 site in 1 country25 target enrollmentStarted: February 2011Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
25
Locations
1
Primary Endpoint
dental plaque PH

Study Overview

Brief Summary

The aim of this study was to determine whether rinsing with water or cleansing teeth after topical fluoride therapy affect the dental plaque pH.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Crossover
Primary Purpose
Prevention
Masking
Single (Outcomes Assessor)

Eligibility Criteria

Ages
21 Years to 29 Years (Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • healthy people (Without any systemic disease)
  • normal unstimulated salivary rate

Exclusion Criteria

  • Active dental caries
  • taking any medication with any effect on saliva rate
  • taking antibiotic (or antibacterial mouth rinses) during last 4 weeks
  • usig fluoride mouth rinses during last 2 weeks.

Outcomes

Primary Outcomes

dental plaque PH

Time Frame: the pH of 48-hour dental plaque was measured using plaque sampling method before (baseline pH) and after sucrose challenge at 5, 10,15,20,30 minutes

Secondary Outcomes

  • maximum pH drop(5,10,15,20 and 30 min after sucrose chalenge)
  • pH recovery time(within 30 min after sucrose challenge)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Fatemeh Mazhari

principal investigator

Mashhad University of Medical Sciences

Study Sites (1)

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