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临床试验/NCT01569165
NCT01569165已完成不适用

Effect of Water Rinsing After APF Application on Dental Plaque Acidogenicity

Mashhad University of Medical Sciences1 个研究点 分布在 1 个国家目标入组 25 人开始时间: 2011年2月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
25
试验地点
1
主要终点
dental plaque PH

研究概览

简要总结

The aim of this study was to determine whether rinsing with water or cleansing teeth after topical fluoride therapy affect the dental plaque pH.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Prevention
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
21 Years 至 29 Years(Adult)
性别
All
接受健康志愿者
是

入选标准

  • •healthy people (Without any systemic disease)
  • •normal unstimulated salivary rate

排除标准

  • •Active dental caries
  • •taking any medication with any effect on saliva rate
  • •taking antibiotic (or antibacterial mouth rinses) during last 4 weeks
  • •usig fluoride mouth rinses during last 2 weeks.

研究组 & 干预措施

washing after 30 min

Experimental

washing with water after 30 min following APF treatment

干预措施: cleansing teeth after topical fluoride therapy (Procedure)

washing after 15 min

Experimental

washing with water after 15 min following APF treatment

干预措施: cleansing teeth after topical fluoride therapy (Procedure)

immediately washing with water

Experimental

immediately washing with water after APF treatment

干预措施: cleansing teeth after topical fluoride therapy (Procedure)

cleansing teeth with cotton roll

Experimental

cleansing teeth with cotton roll immediately following APF treatment

干预措施: cleansing teeth after topical fluoride therapy (Procedure)

no fluoride therapy

No Intervention

control group

结局指标

主要结局

dental plaque PH

时间窗: the pH of 48-hour dental plaque was measured using plaque sampling method before (baseline pH) and after sucrose challenge at 5, 10,15,20,30 minutes

次要结局

  • maximum pH drop(5,10,15,20 and 30 min after sucrose chalenge)
  • pH recovery time(within 30 min after sucrose challenge)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Fatemeh Mazhari

principal investigator

Mashhad University of Medical Sciences

研究点 (1)

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