Effects of Neurodynamic Interventions to Multimodal Physical Therapy in Patients With Multiple Sclerosis

Universidad Rey Juan Carlos1 site in 1 country32 target enrollmentJuly 26, 2018

ConditionsMultiple Sclerosis

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Multiple Sclerosis
Sponsor: Universidad Rey Juan Carlos
Enrollment: 32
Locations: 1
Primary Endpoint: Changes in pressure pain sensitivity
Status: Completed
Last Updated: 7 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

A randomized, parallel-group, clinical trial will be conducted to compare the immediate effects of the inclusion of a neurodynamic intervention into a multimodal physiotherapy program on pressure pain sensitivity, pain and manual dexterity in patients with multiple sclerosis

Registry

clinicaltrials.gov

Start Date

July 26, 2018

End Date

October 4, 2018

Last Updated

7 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Universidad Rey Juan Carlos

Responsible Party

Principal Investigator

César Fernández-de-las-Peñas

Director of Department

Universidad Rey Juan Carlos

Eligibility Criteria

Inclusion Criteria

•a diagnosis of multiple sclerosis according to the modified McDonald criteria;
•symptoms of paresthesia and lack of sensitivity in the upper extremity;
•Expanded Disability Status Scale (EDSS) between 0 and 6.5 points;
•absence of cognitive deficit.

Exclusion Criteria

•any exacerbation of multiple sclerosis during the previous 3 months;
•previous hand surgery or steroid injections treatment in the upper extremity;
•multiple diagnoses on the upper extremity (e.g., cervical radiculopathy);
•cervical, shoulder, or upper extremity trauma;
•other comorbid musculoskeletal medical conditions;
•mini-mental state examination \<25

Outcomes

Primary Outcomes

Changes in pressure pain sensitivity

Time Frame: Baseline and one week after the last treatment session

Pressure pain threshold over the median, ulnar and radial nerves, second metacarpal and tibialis anterior

Secondary Outcomes

Changes in upper extremity pain intensity before and after the intervention(Baseline and one week after the last treatment session)
Changes in light touch detection threshold(Baseline and after treatmentBaseline and one week after the last treatment session)
Changes in manual dexterity(Baseline and one week after the last treatment session)