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临床试验/NCT00313430
NCT00313430已完成不适用

Urinary Concentration and Diluting Ability in Patients With Chronic Renal Disease or Hypertension

Erling Bjerregaard Pedersen1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2004年5月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
50
试验地点
1

研究概览

简要总结

The investigators want to test the hypothesis that patients with chronic renal disease have a poorer ability to preserve water after being thirsty and a poorer ability to excrete water after a load of fluid. They presume that these abilities become poorer when renal insufficiency progresses. The investigators further hypothesize that patients with hypertension also have a decreased ability to concentrate and dilute urine.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients with chronic renal insufficiency, aged between 18 and 65, both men and women
  • Creatinine clearance between 30-59 ml/min
  • Patients with hypertension, aged between 18 and 65, both men and women; hypertension is defined as a mean arterial blood pressure in the daytime that is more than 140/90 mm Hg.
  • Healthy volunteers, aged between 18 and 65, both men and women

排除标准

  • Clinical signs or history of disease in the heart, lungs, liver, brain, and endocrine organs
  • Alcohol abuse
  • Medicine abuse
  • Pregnancy

研究者

发起方
Erling Bjerregaard Pedersen
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Erling Bjerregaard Pedersen

professor, chief physician

Regional Hospital Holstebro

研究点 (1)

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