Phase II Study of De-intensified Treatment (radiation alone) for Human Papilloma Virus-Associated Oropharyngeal Cancer
Phase 2
- Conditions
- resectable human papilloma virus associated locally advanced oropharyngeal cancer
- Registration Number
- JPRN-UMIN000008953
- Lead Sponsor
- Osaka University Graduate School of Medicine, Dept. of Otorhinolaryngology-Head and Neck Surgery
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 39
Inclusion Criteria
Not provided
Exclusion Criteria
1. previously irradiated the same field as currently scheduled 2. presence of active second primary cancer. heterochronic second primary cancers with no evidence of disease more than 36 months and superficial second primary cancers are allowed. 3. presence of active infectious disease or presence of fever above 38 centidegree 4. cases judged as inappropriate 5. T4 or/and N3
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method response rate (defined as the proportion of the patients who achieved completer response and/or complete metabolic response)
- Secondary Outcome Measures
Name Time Method 2-year overall survival rate, 2-year disease specific survival rate, 2-year recurrence free survival rate, 2-year progression free survival rate