Effect of High Intensity Interval Gait Training on Ambulation in MS
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- 6 minute walk test
研究概览
简要总结
Over 90% of persons with MS (pwMS) complain of difficulty with walking. High intensity interval gait training (HIIGT), where persons alternate brief periods of walking at high speeds with periods of rest has been found to improve walking in other neurologic diagnoses. However its impact on pwMS is not known. Most gait training in MS is done continuously at a slower pace. The purpose of this study is to compare the effects of HIIGT to traditional Moderate Intensity Continuous Gait Training (MICGT) in pwMS.
详细描述
Purpose: To determine whether pwMS will have greater improvements in gait with HIIGT as compared to MICGT.
Primary Question: Does HIIGT results in greater improvements in gait parameters in pwMS than MICGT? Secondary question: Will HIIGT result in greater improvements in balance, lower extremity strength, lower extremity range of motion and HR when compared to MICGT in pwMS?
Hypothesis: HIIGT will result in greater improvements in gait parameters in pwMS than MICGT.
Justification: Previous research has shown that MICGT, moderate intensity interval training and high intensity non-gait interval training is effective in pwMS (1)(2). HIIGT has been shown to be effective in persons with stroke (3) but the effects of HIIGT on pwMS are not known.
Outcomes and dissemination of information: We will present our findings at national conferences and submit manuscripts of our findings to the appropriate peer reviewed journal.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Persons diagnosed with Multiple Sclerosis. Rationale:because we are studying effects of the intervention on participant with MS
- •The ability to walk for 6 minutes continuously with or without assistive device. Rationale:we are using the 6MWT as our primary outcome measure
- •The ability to read, understand and sign a consent form so that they are able to understand the study we are doing
- •Above the age of 18 because they have to be able to give consent for the study
- •English speaking as we do not have the resources for translation for the multiple sessions this study entails
排除标准
- •Any cardiopulmonary, orthopedic, or non-MS neurologic disease as we are only examining the effects of MS and need to rule out the impact of other conditions
- •Report of a recent exacerbation. Rationale: the impact of the rationale can interfere with the impact of the independent variables
结局指标
主要结局
6 minute walk test
时间窗: 6 minutes
Distance covered during continuous walking for 6 minutes
次要结局
- Finctional gait assessment(10 minutes)
研究者
Herbert Karpatkin
Associate Professor
City University of New York