Phase II Study of Carboplatin +Docetaxel +Bevacizumab in Chemo-Naive Patients with stage IIIB and IV Non-Squamous Non-Small-Cell Lung Cancer
- Conditions
- Chemo-Naive Patients with stage IIIB and IV Non-Squamous Non-Small-Cell Lung Cancer
- Registration Number
- JPRN-UMIN000004524
- Lead Sponsor
- The Tokyo cooperative oncology group
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 40
Not provided
1)uncontrolled infection or serious medical complications 2)massive,pleural effusion or ascites (accept controllable pleural effusion with OK-432) 3)untreated current brain metastasis 4)severe cardiac disease 5)uncontrollable hypertension 6)receiving anticoagulant drug(except Aspirin under 325mg/day) 7)current or previous histoty ofhemoptysis(2.5ml)due to NSCLC 8)history of hemoptysis(over 1week)or receive oral/i.v. hemostatic drug 9)cavity in tumor 10with great vessel invasion 11)uncontrolled hypertension 12)current or previous(within the last 1 year)history of GI perforation 13)history of myocardial infarction and cerebral infarction 14)interstitial pneumonia or pulmonary fibrosis detectable on CT scan 15)history of drug induced interstitial pneumonia 16)The operation has been scheduled for the examination period 17)history of active double cancer within 5 years 18)history of active psychological disease 19)history of pregnancy or lactation 20)Patients whose participation in the trial is judged to be inappropriate by the attending doctor
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method