Force Enhancement of m. Quadriceps Femoris During and After Excentric Muscle Activity in Vivo by Maximal and Sub-maximal Deliberately Activation.
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Identification of a potential Force enhancement by complex muscle activity with a high relevance for everyday life, for example more agile leg stretching (knee bend).
研究概览
简要总结
Force enhancement (FE) describes the phenomenon of strength potentialization of a muscle cell or the complete muscle during and after active extension compared to the strength of an isometric contraction with same muscle length. The underlying physiological mechanism of this phenomenon is not completely known today. In vitro trials indicate that the interaction of an active and a passive component on the cellular level are responsible for the higher strength measurements. So far FE could be shown in vitro and in vivo on muscle fibers and small human muscles. Further research is needed for verification of the existence of FE in voluntary motor activity in everyday life. In order to approach this objective the investigators will scrutinize the functionality of the deliberately activated musculus (m) quadriceps femoris during and after active extension on the basis of in vivo studies.
详细描述
The research proposal is resubmitted with no amendments made regarding content.
研究设计
- 研究类型
- Observational
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Males without previous muscular or neurophysiological diseases
- •Age between 20 and 40 years
排除标准
- •Previous muscular or neurophysiological diseases
结局指标
主要结局
Identification of a potential Force enhancement by complex muscle activity with a high relevance for everyday life, for example more agile leg stretching (knee bend).
时间窗: 12 months
次要结局
- Evidence of existence of the force enhancement by deliberately activated, great human muscle by sub-maximal activation(12 months)
- Correlation between typ of muscle fiber and force enhancement in vivo(12 months)
- Analysis of the alternation of length of the muscle fiber during and after excentric extension for the differentiated explanation of in vivo mechanism excentric and post-excentric strength(12 months)