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Manual Therapy/Exercises vs. Physiotherapy/Back School vs. Waiting List in Patients With Chronic Low Back Pain

Not Applicable
Terminated
Conditions
Chronic Low-back Pain
Interventions
Behavioral: Manual Therapy/Exercises
Behavioral: Physiotherapy/Back School
Registration Number
NCT05843149
Lead Sponsor
Charite University, Berlin, Germany
Brief Summary

A randomized controlled trial for patients with chronic low back pain with two treatment arms and one waiting list control group. Primary outcome is pain intensity on VAS.

Detailed Description

Not available

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
6
Inclusion Criteria
  • pre-existing and specialist confirmed diagnosis of chronic low back pain for at least 3 months prior to inclusion
  • Average pain intensity with at least 40 mm on the VAS from 0 to 100 mm and pain on at least 5 of 7 weekdays in the last 3 months.

Exclusion criteria:

  • Regular own exercise practice for the treatment of back pain (including yoga and other interventions)
  • Invasive spinal procedures within the past 6 weeks or planned within the next 10 weeks
  • Acute disc herniation (diagnosed within the last 3 months)
  • Congenital deformities of the lumbar spine
  • Rheumatoid arthritis
  • Fibromyalgia
  • Ankylosing spondylitis
  • Severe comorbidities
  • Pregnancy/lactation
  • Current participation in another clinical trial
Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Manual Therapy/ExercisesManual Therapy/ExercisesThree individual therapy sessions and nine group sessions manual therapy/exercises of 60 min. duration under the guidance of a trained therapist.
Physiotherapy/Back SchoolPhysiotherapy/Back SchoolThree individual therapy sessions and nine group sessions physiotherapy/back school of 60 min. duration under the guidance of a trained therapist.
Primary Outcome Measures
NameTimeMethod
Change from baseline in average pain intensity in previous week3 months

Intensity of pain in previous week as measured on a 100 mm visual analog scale (0-100).

Secondary Outcome Measures
NameTimeMethod
Change from baseline for back pain specific disability3 months, 6 months

Use of standardized Roland Morris Disability Questionnaire (RMDQ) to assess back pain specific disability. The scale ranges from 0 to 100, where 0 is the lowest level and 100 is the highest level.

Change from baseline for work productivity3 months, 6 months

Use standardized Work Productivity and Activity Impairment Questionnaire (WPAI) to assess employment status and productivity. The scale ranges from 0 to 100, where 0 is the lowest level and 100 is the highest level.

Change from baseline for pain self-efficacy3 months, 6 months

Use of standardized Pain Self-Efficacy Questionnaire (PSEQ). The scale ranges from 0 to 100, where 0 is the lowest level and 100 is the highest level.

Change from baseline in pain medication use in the previous week3 months, 6 months

Specific self-reported pain medication use in previous week.

Change from baseline for health related quality of life3 months, 6 months

Use of standardized Short Form 36 Health Survey (SF-36). The scale ranges from 0 to 100, where 0 is the lowest level and 100 is the highest level.

Change from baseline in average pain intensity in previous week6 months

Intensity of pain in previous week as measured on a 100 mm visual analog scale (0-100).

Change from baseline in pain bothersomeness in previous week3 months, 6 months

Bothersomeness in previous week as measured on a 100 mm visual analog scale (0-100).

Change from baseline for anxiety and depression3 months, 6 months

Use of standardized Hospital Anxiety and Depression Scale (HADS). The scale ranges from 0 to 100, where 0 is the lowest level and 100 is the highest level.

Trial Locations

Locations (1)

Charite University

🇩🇪

Berlin, Germany

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