Prognostic Factors, Morbidity, Mortality and Long Term Survival in Patients With Neuromuscular Disorders Admitted in Intensive Care Unit
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 800
- 试验地点
- 1
- 主要终点
- ICU mortality
研究概览
简要总结
Muscular dystrophies are neuromuscular disorders with disability. Restrictive pulmonary failure and cardiomyopathy affect prognosis.The investigators aim to establish predictive factors for mortality and morbidity in Intensive care unit (ICU ) and to describe the long term follow up after ICU discharge.
详细描述
Muscular dystrophies are neuromuscular disorders with disability. Restrictive pulmonary failure and cardiomyopathy affect prognosis. Little is known about morbidity and mortality of patients with muscular dystrophies admitted in intensive care unit (ICU).The investigators aim to describe the spectrum of patients with muscular dystrophies admitted in ICU , to establish predictive factors for ICU mortality and morbidity and to describe the long term follow up after ICU discharge.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •admitted in ICU
- •Duchenne muscular dystrophy
- •Becker muscular dystrophy
- •Steinert disease
- •Pompe disease
- •metabolic disease
- •mitochondrial disease
- •congenital myopathy
- •others neuro-muscular diseases
排除标准
- •brain injury
- •minor patient
结局指标
主要结局
ICU mortality
时间窗: 1 month
次要结局
- tracheostomy in ICU(1 month)
- decline of vital capacity after ICU stay(2 years)
- long term survival after ICU stay(5 years)
- predictive factors for re admission in ICU(1 year)
研究者
Abdallah FAYSSOIL
MD PhD
Centre d'Investigation Clinique et Technologique 805