The Australasian Malignant Pleural Effusion (AMPLE) trial - 2: A study to evaluate the effect of aggressive daily versus symptomatic IPC drainage on breathlessness and quality of life in patients with a malignant pleural effusio
Not Applicable
Completed
- Conditions
- Malignant Pleural EffusionRespiratory - Other respiratory disorders / diseasesCancer - Any cancer
- Registration Number
- ACTRN12615000963527
- Lead Sponsor
- Prof YC Gary Lee
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 84
Inclusion Criteria
Patients with a symptomatic MPE in whom fluid drainage is considered appropriate by the managing clinician. A MPE is defined as one in which malignant cells are identified in the pleural fluid or pleural biopsy; or a large exudative pleural effusion without other causes in a patient with known disseminated extra-thoracic malignancy.
Exclusion Criteria
Age <18 yrs; expected survival <3 months; pleural infection; chylothorax; pregnancy or lactation; un-correctable bleeding diathesis; previous ipsilateral lobectomy/pneumonectomy; significant loculations likely to preclude effective fluid drainage; significant visual impairment and inability to consent or comply with the protocol.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method