CTRI/2020/12/029894
Not yet recruiting
未知
Comparing the effectiveness of Dexamethasone versus Methylprednisolone in patients with moderate Covid 19 - A Randomised controlled trial - DMC
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere
- Sponsor
- SRM Medical College Hospital and Research Centre
- Status
- Not yet recruiting
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Hospitalized patients with moderate SARS\-COV\-2 infection laboratory confirmed by RT\-PCR
- •(Moderate COVID 19\- SPO2 \<94% Under room air and requiring supplemental oxygen for hypoxemia
- •Respiratory rate 24\-30/min
- •CRP 50\-100 mg/l
- •Serum ferritin 600\-1500 ng/ml
- •Serum LDH 300\-500 IU/l
- •D Dimer 0\.5\-1\.0 mic/ml
- •IL\-6 20\-100 pg/ml
- •CT chest showing 25\-75% infiltrates)
Exclusion Criteria
- •1\.Patients with mild and severe covid pneumonia
- •2\.Patients who are already on steroid treatment for any underlying condition
- •3\.Patients already started on antivirals
- •4\.Pregnant or lactating women
- •5\.Any known contraindication to short term corticosteroid like severe immunosuppression, HIV infection or any other immunosuppressant usage
Outcomes
Primary Outcomes
Not specified
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