Comparison of Nasal pillow noninvasive positive pressure ventilation and high flow nasal therapy for the treatment and prevention of post extubation failure in intensive care patients

Not Applicable

• Conditions: ICU patients

• Registration Number: JPRN-UMIN000045352
• Lead Sponsor: Department of Anesthesiology and Intensive Care, Faculty of Medicine, Oita University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-09-02
• Study Completion: 2021-12-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 110

Inclusion Criteria

Not provided

Exclusion Criteria

Non-operative patients, patients who did not require ventilatory management for more than 24 hours postoperatively, patients younger than 18 years, patients who used both NP-NPPV and HFNT, tracheostomy, head and neck surgery, significant neurological disorders, patients who used NPPV or HFNT preoperatively

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcomes were respiratory parameters (PO2/FIO2 ratio, PCO2, respiratory rate) and tolerability of each interface immediately after extubation and 24 hours later.

Secondary Outcome Measures

Name	Time	Method
The secondary outcomes were the duration of device use, the rate of device withdrawal after 24 hours, and the incidence of skin injury associated with the interface.