Blood Recirculation and vvECMO

Completed

• Conditions: ARDS; Extracorporeal Membrane Oxygenation

• Registration Number: NCT03200314
• Lead Sponsor: Charite University, Berlin, Germany

Brief Summary

A prospective, observational study will be performed measuring recirculation of blood through a veno-venous Extracoporeal Membrane Oxygenation (vvECMO) in patients with acute respiratory distress syndrome (ARDS) on vvECMO. ECMO blood flow will be adjusted with respect to recirculation.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-06-26
• Study First Submitted QC: 2017-06-26
• Study First Posted: 2017-06-27
• Study Start: 2017-08-13
• Primary Completion: 2018-08-09
• Study Completion: 2018-08-09
• Status Verified: 2020-06
• Last Update Submitted: 2020-06-24
• Last Update Posted: 2020-06-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 21

Inclusion Criteria

• patients aged 18 years or older
• ARDS
• veno-venous ECMO

Exclusion Criteria

• age < 18 years
• hemodynamic instability during measurement of recirculation
• pregnancy
• inability to obtain patient's consent or consent of legal guardian

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Recirculation of vvECMO blood flow	Once within first week after ICU admission during 4 hours	Amount of ECMO blood flow recirculating through the vvECMO circuit

Secondary Outcome Measures

Name	Time	Method
Reduction of vvECMO blood flow	Once within first week after ICU admission during 4 hours	Reduction of vvECMO blood flow if a significant recirculation can be measured
Arterial blood oxygen content after reduction of vvECMO blood flow	Once within first week after ICU admission during 4 hours	Change in arterial blood oygen content after reduction of vvECMO blood flow

Trial Locations

Locations (1)

Charite University, Berlin, Germany; 🇩🇪 Berlin, Germany