Evaluation of Antioxidant and Anti-inflammatory Effect of Matcha Tea Intake on Periodontal Health

Not Applicable

Active, not recruiting

• Conditions: Gingival Disease

• Registration Number: NCT05681325
• Lead Sponsor: Hayder Raad Abdulbaqi

Brief Summary

Aim of the study:

This study aims to evaluate the antioxidant and beneficial effects of matcha tea daily intake on periodontal health.

Objectives:

* To evaluate the salivary level of antioxidants (catalase, total antioxidant capacity) after matcha tea intake compared to green tea over a period of one month.

* To evaluate the clinical periodontal parameters including bleeding on probing (BOP), probing pocket depth (PPD) and plaque index (PI) after matcha tea intake compared to green tea over a period of one month.

* To evaluate the salivary levels of IL-1B after matcha tea intake compared to green tea over a period of one month.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-01-25
• Study First Submitted: 2022-12-11
• Study First Submitted QC: 2023-01-11
• Study First Posted: 2023-01-12
• Status Verified: 2023-12
• Last Update Submitted: 2023-12-22
• Last Update Posted: 2023-12-27
• Primary Completion: 2023-12-30
• Study Completion: 2024-07-12

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• • having at least 20 teeth,

  • underwent no medical treatment during the last 3 months before examination and sampling,
  • non-smoker,
  • no history of systemic disease,
  • gingivitis patient (having >10% bleeding sites with no PPD >3 mm).

Exclusion Criteria

• • wore orthodontic appliances,

  • pregnant or currently in the breast-feeding period,
  • periodontitis patient,
  • smoker,
  • has a history of systemic disease.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
change in salivary level of ant-inflammatory marker	30 Days (baseline to one moth of tea intake)	change in level of interleukin- one beta (IL-1B) in pg/L
change in salivary level of antioxidant marker	30 Days (baseline to one moth of tea intake)	change in level of catalase enzyme in ku/L

Secondary Outcome Measures

Name	Time	Method
change in percentage of bleeding on probing (BOP)	30 Days (baseline to one moth of tea intake)	change in BOP percentage. less percentage means less inflammation in gingival tissue
change in plaque index (PI) scores	30 Days (baseline to one moth of tea intake)	change in PI scores. less scores mean less dental plaque accumulated onto teeth surfaces

Trial Locations

Locations (1)

Universality of Baghdad, College of dentistry; 🇮🇶 Baghdad, Iraq