Fraction of Inspired Oxygen and Atelectasis in Children
Not Applicable
Completed
- Conditions
- Pulmonary Atelectasis
- Registration Number
- NCT02870842
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
Investigators hypothesized that maintaining low fraction of inspired oxygen would be beneficial to prevent anesthesia-induced atelectasis in mechanically ventilated children undergoing general anesthesia.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 86
Inclusion Criteria
- Expected operation time between 1 to 3 hours under general anesthesia
- Mechanically ventilated after endotracheal intubation
Exclusion Criteria
- Cardiac, thoracic, abdominal surgery
- History of surgery on the lungs
- Laparoscopic surgery
- Abnormal preoperative chest radiograph findings including atelectasis, pneumothorax, pleural effusion, and pneumonia
- Considered inappropriate by the investigator
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Incidence of postoperative atelectasis within the first day after the surgery
- Secondary Outcome Measures
Name Time Method Intraoperative incidence of pulse oximetry (SpO2) ≤ 95% (or 10% below the baseline value) from the induction of general anesthesia until the end of the surgery, up to 4 hours Postoperative incidence of respiratory complications within the first day after the surgery Postoperative incidence of fever (≥37.5℃) within the first day after the surgery Incidence of atelectasis after endotracheal intubation from the moment of endotracheal intubation until the end of surgery, up to 4 hours Postoperative incidence of pulse oximetry (SpO2) ≤ 95% (or 10% below the baseline value) within the first day after the surgery
Trial Locations
- Locations (1)
Seoul National University Hospital
🇰🇷Seoul, Korea, Republic of
Seoul National University Hospital🇰🇷Seoul, Korea, Republic of