A comparison between two different oral appliance therapies: Somnodent vs Herbst appliance in patients with mild and moderate OSA; a Randomised Controlled Trial - COSH (comparison OSA patients Somnodent vs Herbst)

Academisch Medisch Centrum0 个研究点目标入组 140 人开始时间: 待定最近更新: 2024年4月29日

适应症

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•+ 18 years and older
•+ Ability to speak, read, and write Dutch.
•+ Ability to follow-up.
•+ Ability to use a computer with internet connection for online questionnaires.
•+ Diagnosis with symptomatic mild or moderate OSA (5 < AHI < 30).
•+ Expected to maintain current lifestyle (sports, medicine, diet, etc.)

•- Untreated periodontal problems, dental pain, and a lack of retention possibilities for an MAD.
•- Medication used/related to sleeping disorders.
•- Evidence of respiratory/sleep disorders other than OSA (eg. central sleep apnea syndrome).
•- Systemic disorders (based on medical history and examination; e.g. rheumatoid arthritis)
•- Temporomandibular disorders (based on the function examination of the masticatory system).
•- Medical history of known causes of tiredness by day, or severe sleep disruption (insomnia, PLMS, Narcolepsy).
•- Known medical history of mental retardation, memory disorders, or psychiatric disorders.
•- Reversible morphological upper airway abnormalities (e.g. enlarged tonsils).
•- Inability to provide informed consent.
•- simultaneous use of other modalities to treat OSA.
•- Previous treatment with a MAD.

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