IRCT20191022045196N2
Recruiting
Phase 2
Evaluating the effect of mirtazapine on anxiety in Parkinson’s disease patients; a randomized double-blinded placebo-controlled clinical trial
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Parkinson’s disease.
- Sponsor
- Shahid Beheshti University of Medical Sciences
- Enrollment
- 64
- Status
- Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Men and women over 17 years old
- •Patient with Parkinson's disease according to UKPDSBB criteria
- •Patient with mild/moderate Parkinson’s disease according to Hoehn and Yahr Scale (HY score \= 1\-3\)
- •Self\-report or clinical diagnosis of anxiety
- •Patients who have signed informed consent to participate in the study
Exclusion Criteria
- •Pregnant and lactating women
- •Parkinson's patients with onset of disease in less than 1 year
- •Unstable medication for Parkinson's disease during the last two weeks
- •Parkinson's patients with DBS
- •Patients with other neurodegenerative diseases like multiple system atrophy (MSA), Huntington's and etc.
- •Patients with major depressive disorder
- •A history of using SSRIs, SNRIs, benzodiazepines and ß\-blockers during the last 4 weeks
- •A history of using MAO inhibitors
- •A history of alcohol and substance abuse
- •A history of acute stress during the last 3 months
Outcomes
Primary Outcomes
Not specified
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