Preterm Premature Rupture Of Membranes between 34 and 37 weeks: EXpectant management versus Induction of Labour

Completed

• Conditions: Premature rupture of the membranes; Pregnancy and Childbirth

• Registration Number: ISRCTN29313500
• Lead Sponsor: The Netherlands Organisation for Health Research and Development (ZonMw) (The Netherlands)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2007-02-13
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 520

Inclusion Criteria

Pregnant women with PPROM at a gestational age from 34 + 0/7 until 37 weeks who have given informed consent.

Exclusion Criteria

1. Foetal distress
2. Major foetal anomalies
3. Meconium stained amniotic fluid
4. Maternal infection at entry
5. Monochorionic Diamniotic (MCDA) multiple pregnancy
6. Multiple pregnancy, first child breech presentation
7. Previous caesarean section
8. Diabetes mellitus (defined as use of insulin)
9. Renal disease (inluding Systemic Lupus Erythematosus [SLE])
10. Seropositive for Human Immunodeficiency Virus (HIV)
11. Haemolysis, Elevated Liver, Low Platelet (HELLP)/severe pre-eclampsia
12. Oliguria less than 500 ml/24 hours

Study & Design

• Study Type: Interventional
• Study Design: Not specified