Assessing Women's Attitudes About the Risk of Infertility Related to Adjuvant Therapy for Early Breast Cancer

Not Applicable

Completed

• Conditions: Breast Cancer; Psychosocial Effects of Cancer and Its Treatment; Sexual Dysfunction and Infertility; Sexuality and Reproductive Issues

• Registration Number: NCT00062400
• Lead Sponsor: European Organisation for Research and Treatment of Cancer - EORTC

Brief Summary

RATIONALE: Adjuvant therapy given after surgery for early breast cancer may cause infertility. Assessing young women's attitudes and feelings about the risk of infertility may help improve the ability to plan effective treatment.

PURPOSE: This clinical trial is studying young women's attitudes and feelings about the risk of infertility related to adjuvant therapy for stage I or stage II breast cancer.

Detailed Description

OBJECTIVES:

* Determine the attitude toward the risk of infertility related to adjuvant therapy in women with early breast cancer.

* Correlate, if possible, the patient's attitude with the fact that the patient already has children or the time interval between the date of breast cancer diagnosis and the date of study participation.

OUTLINE: This is a multicenter study.

Patients complete a questionnaire administered by a nontreating physician.

PROJECTED ACCRUAL: A total of 385 patients will be accrued for this study.

Study Timeline

• Study Start: 2003-05
• Study First Submitted: 2003-06-05
• Study First Submitted QC: 2003-06-05
• Study First Posted: 2003-06-06
• Primary Completion: 2008-06
• Status Verified: 2013-10
• Last Update Submitted: 2013-10-23
• Last Update Posted: 2013-10-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 385

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Patients who would agree to have chemotherapy if it reduces their chances of having children as assessed by questionnaire

Trial Locations

Locations (27)

Centre Hospitalier Etterbeek Ixelles; 🇧🇪 Brussels, Belgium

Azienda Istituti Ospitalieri; 🇮🇹 Cremona, Italy

Clinica Alemana; 🇨🇱 Santiago, Chile

Medical University of Gdansk; 🇵🇱 Gdansk, Poland

Inselspital Bern; 🇨🇭 Bern, Switzerland

Klinikum der J.W. Goethe Universitaet; 🇩🇪 Frankfurt, Germany

Academisch Medisch Centrum at University of Amsterdam; 🇳🇱 Amsterdam, Netherlands

Arnhems Radiotherapeutisch Instituut; 🇳🇱 Arnhem, Netherlands

Hospital Militar; 🇨🇱 Santiago, Chile

University Hospital Rebro; 🇭🇷 Zagreb, Croatia

Marmara University Hospital; 🇹🇷 Istanbul, Turkey

Universitatsklinikum Heidelberg; 🇩🇪 Heidelberg, Germany

American University of Beirut Medical Center; 🇱🇧 Beirut, Lebanon

Instituto Nacional de Enfermedades Neoplasicas; 🇵🇪 Lima, Peru

Instituto Portugues de Oncologia de Francisco Gentil - Centro Regional de Oncologia de Lisboa, SA; 🇵🇹 Lisboa, Portugal

CHU Liege - Domaine Universitaire du Sart Tilman; 🇧🇪 Liege, Belgium

Centro di Riferimento Oncologico - Aviano; 🇮🇹 Aviano, Italy

Ospedale Alessandro Manzoni; 🇮🇹 Lecco, Italy

Western Infirmary; 🇬🇧 Glasgow, Scotland, United Kingdom

Instituto de Radiomedicina; 🇨🇱 Santiago, Chile

Institut Jules Bordet; 🇧🇪 Brussels, Belgium

Algemeen Ziekenhuis Sint-Augustinus; 🇧🇪 Wilrijk, Belgium

Groote Schuur Hospital; 🇿🇦 Cape Town, South Africa

Institute of Oncology and Radiology of Serbia; 🇷🇸 Belgrade, Serbia

Ospedale Beata Vergine; 🇨🇭 Mendrisio, Switzerland

Kantonsspital - St. Gallen; 🇨🇭 St. Gallen, Switzerland

European Institute of Oncology; 🇮🇹 Milan, Italy