Evaluation of iPRF With Vit.D As an Adjunct to Non-Surgical Therapy in the Treatment of Stage III Periodontitis

Phase 2

Not yet recruiting

• Conditions: Periodontal Pocket

• Registration Number: NCT06570200
• Lead Sponsor: Cairo University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-8-15
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Not yet recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Inclusion Criteria:<br><br> 1. Patients with healthy systemic condition.<br><br> 2. Adult patients ? 18 years old.<br><br> 3. Patients with Stage III periodontitis.<br><br> 4. Patients accept 3-month follow-up period (cooperative patients).<br><br> 5. Patients provide an informed consent.<br><br>Exclusion Criteria:<br><br> 1. Presence of prosthetic crowns.<br><br> 2. Extensive interproximal restorations.<br><br> 3. Periodontal therapy within the last 12 months.<br><br> 4. Having undergone surgical periodontal therapy or undergoing orthodontic treatment.<br><br> 5. Ongoing drug therapy that might have an impact on the clinical signs and symptoms of<br> periodontitis.<br><br> 6. The use of antibiotics or anti-inflammatory drugs 3-month prior to the procedure and<br> till the end of 6-month of follow-up.<br><br> 7. Smokers.<br><br> 8. Pregnant females.

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
pocket depth reduction

Secondary Outcome Measures

Name	Time	Method
clinical attachment level (CAL) gain;Plaque index;Bleeding on probing (BOP);Gingival Marginal Level (GML);Post-operative Pain;Treatment time taken for each groups;degree of bone fill or loss