Musculoskeletal problems following critical illness
- Conditions
- Musculoskeletal health state of intensive care unit survivorsMusculoskeletal Diseases
- Registration Number
- ISRCTN24998809
- Lead Sponsor
- Oxford University Hospitals NHS Trust
- Brief Summary
2023 Protocol article in https://pubmed.ncbi.nlm.nih.gov/36731924/ (added 03/02/2023) 2024 Results article in https://doi.org/10.1111/anae.16285 (added 25/07/2024)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 334
Patients who have been admitted to ICU for 48 hours or more
1. Patients who are judged to lack capacity at the time of consent as defined by the Mental Capacity Act (2005)
2. Proven or suspected acute primary brain pathology, spinal cord injury or other neuromuscular disease resulting in proven or prolonged weakness
3. Admitted to the intensive care unit with musculoskeletal complications or trauma
4. Patients who were dependent for activities of daily living in the month prior to current intensive care unit admission (gait aids are acceptable)
5. Patients who have a palliative diagnosis/treatment pathway
6. Prisoners
7. Patients with no fixed abode
8. Patients who are unable to communicate clearly in English over the telephone for 20 minutes
9. Patients refusing consent
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Musculoskeletal health state measured using the Musculoskeletal Health Questionnaire (MSK-HQ) at 6 months
- Secondary Outcome Measures
Name Time Method Measured at 6 months:<br>1. Health-related quality of life measured using the EuroQol 5D (EQ-5D)<br>2. Anxiety and depression measured using the Hospital Anxiety and Depression Scale (HADS)<br>3. Subjective distress measured using the Impact of Events Scale-Revised (IES-R)<br>4. Employment measured using an employment questionnaire