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临床试验/NL-OMON40718
NL-OMON40718撤回不适用

Thiazide diuretics versus calcium channel blockers for the treatment of calcineurin inhibitor-induced hypertension in patients with psoriasis or eczema: a single-center randomized cross-over trial. - TT-study Dermatology

Erasmus MC, Universitair Medisch Centrum Rotterdam0 个研究点目标入组 22 人开始时间: 待定最近更新:

试验速览

阶段
不适用
状态
撤回
入组人数
22

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 至 99(—)

入选标准

  • * Treatment with cyclosporine
  • * MDRD-GFR * 30 ml/min
  • * Systolic blood pressure > 140 mmHg but < 180 mmHg during 24-hours blood pressure measurement
  • * Stable background antihypertensive drugs (i.e., no anticipated change in dose during the study period)
  • * 18 years or older

排除标准

  • * MDRD-GFR < 30 ml/min
  • * Serum sodium < 136 mmol/l
  • * Serum potassium < 3.5 mmol/l
  • * Proteinuria > 1.0 g/10 mmol creatinine
  • * Systolic blood pressure < 140 mmHg during 24-hour blood pressure measurement
  • * The use of co-trimoxazol or prednisone
  • * Incapacitated subjects
  • * Pregnancy
  • * Simultaneous use of thiazides and calcium channel blockers.
  • * Use of loopdiuretics
  • * Pre-existent hypertension
  • * Elevated uric acid levels during the use of thiazide diuretics

研究者

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