Transarterial Chemoembolization with Drug-Eluting Beads Loaded with Doxorubicin for the Treatment of Metastatic Breast Cancer to the Liver: a pilot study
Phase 2
- Conditions
- liver metastases breast cancer10027476
- Registration Number
- NL-OMON37702
- Lead Sponsor
- Antoni van Leeuwenhoek Ziekenhuis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 10
Inclusion Criteria
Patients with biopsy proven liver dominant ( over 50% volume) metastasis of breast carcinoma
Exclusion Criteria
1: significant extrahepatic disease representing an eminent life-threatening outcome
2: more than 75% of hepatic parenchymal involvement
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Technical feasibility of the treatment protocol, including: adequate pain<br /><br>relief during the procedure, the loading of beads, angiographic success and<br /><br>procedure-related toxicity ( defined as procedure related complications that<br /><br>makes hospitalisation longer than 48 hours post-procedure necessary. Proportion<br /><br>of patients completing scheduled treatment plan.</p><br>
- Secondary Outcome Measures
Name Time Method <p> Response rate ( according to RECIST), time to progression, and overall<br /><br>survival .</p><br>