DRKS00016852已完成不适用
Berlin Longterm Observation of Vascular Events - Pilot study - BeLOVE - Pilot study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 2,248
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 one（—）
- 性别
- All
入选标准
- •provision of signed and dated informed consent form
- •2)declared willingness to take part in study procedures and to be contacted again for further
- •follow-up examinations
- •3)persons of any sex and gender, aged 18 years or above at the time of acute event or study
- •4)general health status is acceptable for participation in a study
- •5)clinical diagnosis of one or more of the following diseases:
- •A) acute heart failure (trigger event), defined by:
- •i) dyspnoe NYHA IIIb or IV and NTproBNP = 300 pg/nl OR
- •MRproANP = 120 pmol/l, AND
- •ii)evidence of pitting peripheral edema or radiological or clinical signs of
- •of pulmonary congestion, AND
- •iii)Need for i.v.-administration or dose escalation of diuretic therapie
- •equivalent to furosemid 40 mg or torasemid of 10 mg.
- •B) acute coronary syndrome (trigger event), defined by:
- •i) acute cardiac chest pain, or angina equivalent consistent with moderate to high-
- •risk unstable angina or myocardial infarction, lasting more than 10 minutes
- •duration during72 hours before invasive examination, AND
- •ii) evidence for ACS requiring catheterization documented by
- •(1)elevated enzymes (CK-MB or hs-troponin i/T >99th percentile or in-
- •/decrease) AND/OR
- •(2)ECG with ST-depression >1mm in 2 or more contiguous leads after the
- •J-point AND/OR
- •(3)transient ST-elevation >1mm in 2 or more contiguous leads lasting
- •<30 min OR
- •(4)STE-ACS with onset <24 hours previously and chest pain > 30 min
- •ST-elevation > 1mm in 2 or more contiguous leads or new left bundle block
- •C) acute cerebrovascular disorders (trigger event), defined by:
- •i) a transient ischemic attack (TIA) with clinical restitution within 24h AND
- •initial neurological deficit verified by a neurologist OR ABCD2-Score >= 3 OR
- •visibleDWI-lesion (MRI) OR the main hospital diagnosis of Amaurosis fugax
- •ii) Ischemic stroke including retinal central artery occlusion
- •iii) stroke caused by non-traumatic intracerebral hemorrhage
- •iv) stroke caused by cerebral venous thrombosis
- •D) acute kidney injury while hospitalized, that occurred 3-8 days before study inclusion
- •(trigger event), defined by:
- •i) >= 2fold increase in creatinine compared to a respective value during a presumed
- •or documented time period (stage 2 or 3 acute kidney injury according to KDIGO)
- •ii) persistence of the increased value for at least 72 hrs
- •E) diabetes mellitus type 2 (at day 60)
- •i) known diabetes mellitus type 2 characterized by
- •(1) pathological findings in oral glucose tolerance test, OR
- •(2) documented HbA1c >= 6.5%, OR
- •(3) Intake of any antidiabetic medication
- •ii) prediabetes with high cardiovascular risk, characterized by
- •(1)HbA1c >5.7% and <6.5% AND an ESC score >= 5
排除标准
- •1) lack of capacity to give informed consent
- •2) pregnancy or lactation
- •3) life expectancy < 6 months due to non-cardio-/cerebrovascular diseases or conditions
- •4) organ transplanted
- •5) Lack of health insurance
研究者
相似试验
招募中
不适用
Berlin Longterm Observation of Vascular EventsI21I61I63N17H34.1G45.0G45.1G45.2G45.3G45.9I11.0I13.0I13.2I13.9I42I50I50.13I50.14I50.19I50.9I10.0I10.1I10.9E78.0E78.1E78.2E78.5I70.2I70.8I25.1N18.3N18.4N18.5H35.0H36.0G63.2Intracerebral haemorrhageDiabetic retinopathyAcute renal failureVertebro-basilar artery syndromeCarotid artery syndrome (hemispheric)Multiple and bilateral precerebral artery syndromesAmaurosis fugaxTransient cerebral ischaemic attack, unspecifiedHypertensive heart disease with (congestive) heart failureHypertensive heart and renal disease with (congestive) heart failureHypertensive heart and renal disease with both (congestive) heart failure and renal failureHypertensive heart and renal disease, unspecifiedHeart failure, unspecifiedPure hypercholesterolaemiaPure hyperglyceridaemiaMixed hyperlipidaemiaHyperlipidaemia, unspecifiedAtherosclerosis of arteries of extremitiesAtherosclerosis of other arteriesAtherosclerotic heart diseaseChronic kidney disease, stage 3Chronic kidney disease, stage 4Chronic kidney disease, stage 5Background retinopathy and retinal vascular changesDiabetic polyneuropathyCerebral infarctionCentral retinal artery occlusionHeart failureAcute myocardial infarctionCardiomyopathyDRKS00023323Charité Campus Charité Mitte8,000
已完成
不适用
Study of vascular anatomy, blood flow evaluation, breast morphology evaluation, and complications in breast reconstruction with abdominal perforator flapBreast cancer: cases of total mastectomy followed by breast reconstruction using a deep inferior epigastric artery perforator flapJPRN-UMIN000047153Juntendo University500
进行中（未招募）
不适用
Study of vascular complications in critically ill patients with coronavirusSevere Acute Respiratory SyndromeCoronavirus infectionsC01.925.782.600.550.200C01.748.730RBR-4qjzh7Disciplina de Cirurgia Vascular e Endovascular da Universidade Federal de São Paulo
撤回
不适用
The outcome of a new vascular stent in patients with arterial disease in the legsPeripheral Arterial DiseaesFemoro-popliteal Arterial DiseaseChronic Limb IschaemiaClaudicationCritical Limb IschaemiaCardiovascular - Diseases of the vasculature and circulation including the lymphatic systemACTRN12618001310257Dr. Vikram Puttaswamy (Investigator)200
招募中
不适用
Prospective angioscopic Observation of vascular wall Re-intimal Coverage over DES IN the Infra-inguinal lesioPeripheral Arterial DiseaseJPRN-UMIN000018862Kansai Rosai Hospital50