Scrutinizing and Promoting Mindfulness Via New Technologies: Smartphone-based Assessment and Micro-intervention and Functional Magnetic Resonance Imaging (fMRI) (-Neurofeedback)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 84
- 试验地点
- 2
- 主要终点
- Blood oxygenation level dependent (BOLD) Signal assessed by MRI
研究概览
简要总结
The overall goal of the outlined study is to scrutinize and to promote mindfulness via new technologies using a combination of smartphone-based assessment and micro-interventions, fMRI and real-time fMRI-neurofeedback.
详细描述
The overall goal of the outlined study is to scrutinize and to promote mindfulness via new technologies using a combination of smartphone-based assessment and micro-interventions, fMRI and real-time fMRI-neurofeedback. More specifically, we aim to i) evaluate whether smartphone-based micro-interventions affect mindfulness, stress, and mood, ii) evaluate whether mindfulness, its neural substrate, and related mental and physiological functions can be modified by training volitional control over brain activity by means of real-time functional magnetic resonance imaging neurofeedback (RT-fMRI-NF), iii) differentiate neural activation patterns during mindfulness vs. mind wandering.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Sequential
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Right-handedness
- •Ability to participate in study procedures
排除标准
- •Color-Blindness
- •Present or past psychological or psychiatric therapy
- •Presence of cardiovascular disease
- •History of major cerebral injury
- •Medical MRI contraindication
结局指标
主要结局
Blood oxygenation level dependent (BOLD) Signal assessed by MRI
时间窗: On 1 day, which is the laboratory assessment day (scheduled 1 day subsequent to the last of the 10 smartphone-based micro-intervention days)
Blood oxygenation level dependent (BOLD) signal assessed via functional magnetic resonance imaging
Subjective mood assessed by Multidimensional Mood State Questionnaire
时间窗: Daily, during smartphone-based micro-interventions (duration: 10 days); on 1 day, which is the laboratory assessment day (scheduled 1 day subsequent to the last smartphone-based micro-intervention days)
Subjective mood, assessed via Multidimensional Mood State Questionnaire (MDMQ)
Subjective stress reactivity assessed by Visual Analog Scale
时间窗: Daily, during smartphone-based micro-interventions (duration: 10 days); on 1 day, which is the laboratory assessment day (scheduled 1 day subsequent to the last smartphone-based micro-intervention days)
Subjective stress reactivity, assessed via Visual Analog Scale (VAS)
State mindfulness assessed by State Mindfulness Scale
时间窗: Daily, during smartphone-based micro-interventions (duration: 10 days); on 1 day, which is the laboratory assessment day (scheduled 1 day subsequent to the last smartphone-based micro-intervention days)
State mindfulness, assessed via State Mindfulness Scale (SMS)
次要结局
- Working Memory assessed by N-back task test(On 1 day, which is the laboratory assessment day (scheduled 1 day subsequent to the last of the 10 smartphone-based micro-intervention days))
- Emotional reactivity assessed by emotion recognition task(On 1 day, which is the laboratory assessment day (scheduled 1 day subsequent to the last of the 10 smartphone-based micro-intervention days))
- Cognitive flexibility assessed by computer version of Wisconsin card sorting Task test(On 1 day, which is the laboratory assessment day (scheduled 1 day subsequent to the last of the 10 smartphone-based micro-intervention days))