Comparison of Optic Nerve Sheath Diameter Measured by Ultrasonography Before and After Ventriculoperitoneal Shunt Surgery in Adult Patients With Hydrocephalus

Withdrawn

• Conditions: Hydrocephalus
• Interventions: Device: ultrasonographic measurement of optic nerve sheath diameter

• Registration Number: NCT02663947
• Lead Sponsor: Yonsei University

Brief Summary

Hydrocephalus is a disturbance of cerebrospinal fluid production, flow and absorption leading to intracranial hypertension. Assessment of the change in intracranial pressure after ventriculoperitoneal shunt surgery is important in guiding appropriate postoperative management. The optic nerve sheath diameter measured using ultrasonography has been verified as a non-invasive indicator of intracranial hypertension in various clinical studies. The investigators hypothesized that a change in optic nerve sheath diameter detected through ultrasonography could help ascertain a reduction in intracranial pressure following ventriculoperitoneal shunt surgery in adult patients without the risk of serious complications.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-01
• Study First Submitted: 2016-01-21
• Study First Submitted QC: 2016-01-25
• Study First Posted: 2016-01-26
• Primary Completion: 2016-11
• Study Completion: 2017-01
• Status Verified: 2019-01
• Last Update Submitted: 2019-01-15
• Last Update Posted: 2019-01-17

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Adult patients (20-90 years of age, ASA physical status 3 or less) who are scheduled for elective ventriculoperitoneal shunt surgery with non-communicating hydrocephalus and communicating hydrocephalus except for normal-pressure hydrocephalus
• Non-communicating hydrocephalus is defined as a pattern of ventricular system or at the level of the fourth ventricle's outlets by lesions including tumor, giant aneurysm, or aqueductal stenosis.
• Communicating hydrocephalus is defined as paraventricular enlargement resulting from postoperative complication after cranial surgery, meningitis, subarachnoid or intracerebral hemorrhage.

Read More

Exclusion Criteria

• Patients with previous history of shunt operation, ocular disease and ocular surgery
• Patients with anatomical or functional abnormality of optic nerve
• emergency patient

Read More

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
ultrasound group	ultrasonographic measurement of optic nerve sheath diameter	ultrasonographic measure for optic nerve sheath diameter

Primary Outcome Measures

Name	Time	Method
ultrasonographic measurement of optic nerve sheath diameter	30 minutes

Trial Locations

Locations (1)

Associate Professor Department of Anesthesiology and Pain Medicine; 🇰🇷 Seoul, Korea, Republic of