Effect of electroacupuncture preconditioning on postoperative delirium and plasma circRNA-089763 expression in elderly patients

Phase 1

• Conditions: postoperative delirium

• Registration Number: ITMCTR2100005112
• Lead Sponsor: Beijing Hospital of Traditional Chinese Medicine, Capital Medical University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1.Patients undergoing general anesthesia for elective non-cardiac surgery in our hospital;
2.Aged 65 to 80 years;
3.American Society of Anesthesiologists (ASA) grade II ~ III (see Table 1), no severe respiratory, circulation, liver, kidney, coagulation function abnormalities;
4.Expected operation duration >2h;
5.Surgery grade 3-4;
6.Concise Intelligence Scale (MMSE) score Illiterate (uneducated)>17, primary school >20, secondary school and above >24.

Exclusion Criteria

1.Preoperative patients with psychiatric and neurological diseases;
2.Patients with severe respiratory, circulatory or other system dysfunction;
3.Patients with systemic acute and chronic infection before surgery;
4.Low compliance, severe hearing, visual impairment, reading, understanding disorders;
5.Patients with pacemakers;
6.History of drug abuse.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of postoperative delirium;

Secondary Outcome Measures

Name	Time	Method
Security Index;The expression of circ-089763;