The immersive virtual memory task: application of immersive Virtual Reality to investigate spatial memory deficits in neurological disorders
- Registration Number
- DRKS00024005
- Lead Sponsor
- Tagesklinik für Kognitive Neurologie, Universitätsklinikum Leipzig
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 35
Subjects of any gender with acquired brain injury aged between 18 and 80 years can participate in the planned study. The diagnosis must be confirmed according to the respective disease-specific diagnostic criteria. In addition, the willingness and ability to participate must be fulfilled and a written informed consent must be available. There must be sufficient knowledge of German, linguistic comprehension ability and adequate visual ability.
Subjects with acute psychosis, those suffering from dizziness symptoms or with a history of alcohol or drug abuse cannot participate. Furthermore, subjects who are incapable of giving consent, who lack consent to report any incidental findings, who do not give written consent to participate, or who withdraw consent may not participate. Furthermore, subjects suffering from epilepsy may only participate if the last epileptic seizure occurred more than two years ago and stable medication can be established. Participating women must not be pregnant, planning a pregnancy or breastfeeding.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method (1) The newly developed VR task, the imVMT, is externally validated using neuropsychological test procedures to measure spatial memory. The primary outcome measure is the correlation between performance on the imVMT, measured by mean deviation error (MDE), and standardized neuropsychological test procedures (Rey-Osterrieth Complex Figure Test, immediate recall; Visual and Verbal Memory Test, City Map subtest, immediate recall).
- Secondary Outcome Measures
Name Time Method (2) Determination of convergent and divergent validity with further neuropsychological test procedures (e.g. Montreal Cognitive Assessment, Trail Making Test, Corsi Block Tapping) and investigation of specificity.<br>(3) Evaluation of the influence of the task variables number of objects (3, 5, 7 objects) and rotation (90°, 180°, 270°) on the MDE.<br>(4) Evaluation of the influence of the task variables number of objects (3, 5, 7 objects) and rotation (90°, 180°, 270°) on the processing time<br>(5) Investigation of feasibility and acceptance of the immersive VR task measured by questionnaires (Simulator Sickness Questionnaire, Motion Sickness Susceptibility Questionnaire) and behavioral observations.<br>(6) System evaluation of the immersive VR task in terms of immersion (Immersive Tendencies Questionnaire, Presence, (Presence Questionnaire. Self-Presence Questionnaire), motivation and usability (VRUSE).