Comparative Evaluation Of The Efficacy Of Microneedling With The Injectable Platelet- Rich Fibrin Versus Microneedling With The Concentrated Platelet-Rich Fibrin In The Management Of The Thin Gingival Phenotype - A Split Mouth Randomized Clinical Trial.
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 11
- 试验地点
- 1
- 主要终点
- The aim of the study is to compare and evaluate the efficacy of microneedling with the injectable platelet-rich fibrin versus microneedling with the concentrated platelet-rich fibrin in the management of the thin gingival phenotype
研究概览
简要总结
The success of restorative dental procedures and periodontal health are significantly influenced by the gingival phenotype which is defined by gingival thickness GT and keratinized tissue width KTW Particularly vulnerable to gingival recession cosmetic issues and a poor reaction to inflammatory or mechanical stress are thin gingival phenotypes
Phenotype modification therapies PhMT have consequently become increasingly important in contemporary dentistry Though they are thought to be the best option traditional gingival augmentation techniques such connective tissue grafts CTGs are invasive necessitate surgical skill and frequently have poor patient compliance
Micro needling MN and other minimally invasive procedures have become substitutes in recent years Through regulated micro injuries microneedling increases the production of collagen and promotes tissue regeneration whereas platelet rich fibrin PRF enhances tissue repair and regeneration by releasing growth factors
Advanced variants of PRF such as injectable PRF i PRF and concentrated PRF C PRF are more successful at tissue regeneration because they contain larger concentrations of platelets and leukocytes C PRF with its greater regenerative capacity has not been thoroughly compared to i PRF in the context of thin gingival phenotypic alteration despite the fact that i PRF has been examined in conjunction with microneedling
This study aims to compare the efficacy of microneedling combined with i PRF versus microneedling combined with C PRF in modifying thin gingival phenotypes By evaluating changes in gingival thickness and keratinized tissue width this research seeks to provide evidence for the most effective minimally invasive approach to gingival augmentation
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Double
入排标准
- 年龄范围
- 18.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients in the age group 18 to 45 years from both genders without any blood disorder willing to undergo treatment with informed consent were included Sites with thin gingival phenotype gingival thickness less than 1 point 5mm in maxillary and mandibular canine and premolar region Plaque index PI less than 1 Gingival index GI less than 1 Bleeding on probing score of less than 10 percent will be included in the study.
排除标准
- •Patients undergoing active orthodontic treatment Taking any medication that may cause gingival enlargement Bruxism Any previous history of periodontitis or periodontal therapy Pregnant or lactating women Use of tobacco in any form Taking any blood thinners Patients under Aspirin medication Pre-existing mucogingival deformities.
结局指标
主要结局
The aim of the study is to compare and evaluate the efficacy of microneedling with the injectable platelet-rich fibrin versus microneedling with the concentrated platelet-rich fibrin in the management of the thin gingival phenotype
时间窗: The outcome is assessed at baseline 3 months and 6 months
次要结局
- 1)To assess the Gingival thickness following microneedling with i-PRF & microneedling with C-PRF in thin gingival phenotype.(2)To assess the Keratinized tissue width following microneedling with i-PRF & microneedling with C-PRF in thin gingival phenotype)
研究者
Dr Surabhi S Gowda
KVG Dental college and hospital