Quantitative study: low diuresis rate a possible influencer of abnormal bladder sensations in Overactive Bladder patients?

• Conditions: Overactive Bladder; Urgency complaints; 10004994

• Registration Number: NL-OMON35430
• Lead Sponsor: Medisch Universitair Ziekenhuis Maastricht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 50

Inclusion Criteria

Patients with OAB (over 18 years) diagnosed by their urologist using the criteria of more than 8 micturitions on three consecutive days. While investigation
starts they will not use any anticholinergic or other therapy. Patients on anticholinergic therapy will be asked to stop this therapy for at least
10 days before they enter the first session. Well versed in Dutch.;Healthy subjects:
• Men and women
• Under 65 years of age)
• Over 18 years of age
• Well versed in Dutch

Exclusion Criteria

Older dan 65 years
Congestive heart disease or history of heart failure
Presence of urinary tract infection. These patients will be treated by antibiotics.
History or (current) neurologic disease (not including good regulated diabetes)
Stress urinary incontinence
Postmicturition residual volume of > 75 cc

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The difference in diuresis between session 1 and 2. The (difference in) voided<br /><br>volumes during the different sessions and the (difference in) duration time of<br /><br>the different sessions. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Relieve of urgency and frequency symptoms of OAB patients (difference in<br /><br>introspection curve0 by a non-invasive advice to increase diuresis rate.<br /><br>Information to validate non-invasive therapy to decrease symptoms of OAB<br /><br>patients</p><br>