Comparison of Anwar and Melles Techniques in Deep Anterior Lamellar Keratoplasty (DALK) for Keratoconus Patients

Not Applicable

Completed

• Conditions: Keratoconus
• Interventions: Procedure: Anwar; Procedure: Melles

• Registration Number: NCT00850148
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

This study will be performed on patients who come to labbafinejad ophthalmic clinic from 20 March 2008. Keratoconus diagnosis will be determined by clinical finding in slit lamp, keratometery and topographic characteristics. Patients will be randomly placed in group A and B. In group A, Anwar surgical method and in B, Melles surgical method, will be done. This is not a blind study due to surgeons' knowledge. All patients will receive Btamethazone drop and Chloramphenicol every 6 hours and will be tapered in two months. In the end anatomical results, complications, BCVA, UCVA, astigmatism, endothelial cell numbers will be compared in two groups by using specular microscopy. Contrast sensivity, central corneal diameter, interface wrinkling and opacity will be measured by metrovison, Confoscan, Photoslit in months 3, 6, 12, respectively and will be evaluated afterwards.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-05
• Status Verified: 2009-02
• Study First Submitted: 2009-02-23
• Study First Submitted QC: 2009-02-23
• Study First Posted: 2009-02-24
• Primary Completion: 2009-06
• Study Completion: 2009-09
• Last Update Submitted: 2012-01-04
• Last Update Posted: 2012-01-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• patients with keratoconus
• 15<age<45
• contact lens intolerance

Exclusion Criteria

• Having a history of any other ophthalmic or systemic problem
• Central corneal scar
• descemet's membrane detachment

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Anwar	Anwar	-
Melles	Melles	-

Trial Locations

Locations (2)

Ophtalmic Research Centre; 🇮🇷 Tehran, Iran, Islamic Republic of

Farid Karimian,MD; 🇮🇷 Tehran, Iran, Islamic Republic of