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Clinical Trials/NCT05445271
NCT05445271UnknownNot Applicable

The Effects of Endotracheal Intubation or Laryngeal Mask Applications on Optic Nerve

Kahramanmaras Sutcu Imam University0 sites90 target enrollmentStarted: July 1, 2022Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Sponsor
Enrollment
90
Primary Endpoint
Optic nerve sheath diameter measurement at pediatric patients

Study Overview

Brief Summary

Endotracheal intubation and laryngeal mask are generally applied to secure the airway during general anesthesia. There is a widespread opinion among anesthesiologists that endotracheal intubation increases intracranial pressure. Since there were no non-invasive methods measuring intracranial pressure in the past, adequate studies on this subject could not be done. With this measurement, we aimed to show whether ETT or LMA applications have effects on intracranial pressure.

Detailed Description

In normal pediatric patients with closed fontanelles, the contents of the central nervous system are almost compressed into the skull and spinal canal. Intracranial pressure is created and constant by the total volume of brain, CSF, and blood within the skull. Increased intracranial pressure can be measured with an intraventricular catheter, transducers, and a subarachnoid bolt. By measuring the diameter of the optic nerve sheath with ultrasonography, we can find out whether there is an increase in intracranial pressure non-invasively.

Endotracheal intubation and laryngeal mask are generally applied to secure the airway during general anesthesia. There is a widespread opinion among anesthesiologists that endotracheal intubation increases intracranial pressure. Since there were no non-invasive methods measuring intracranial pressure in the past, adequate studies on this subject could not be done. With this measurement, we aimed to show whether ETT or LMA applications have effects on intracranial pressure.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Diagnostic
Masking
Double (Participant, Investigator)

Eligibility Criteria

Ages
2 Years to 18 Years (Child, Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Patients aged 2-18 years
  • Patients undergoing general anesthesia
  • Patients who agreed to be included

Exclusion Criteria

  • Those with any eye pathology
  • Those with intracranial pathology

Outcomes

Primary Outcomes

Optic nerve sheath diameter measurement at pediatric patients

Time Frame: 6 months

to show whether endotracheal intubation or LMA applications with optic nerve sheath diameter measurement, which is a completely non-invasive method, have effects on intracranial pressure.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Kahramanmaras Sutcu Imam University
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Feyza Calisir

Assistant professor

Kahramanmaras Sutcu Imam University

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