The CUBA Study - Cane Use and Bone marrow lesions in knee osteoArthritis

Not Applicable

Recruiting

• Conditions: Osteoarthritis, knee; Musculoskeletal - Osteoarthritis; Physical Medicine / Rehabilitation - Physiotherapy

• Registration Number: ACTRN12614000909628
• Lead Sponsor: niversity of Melbourne

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-08-26
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Aged>50;
Knee pain on most days of the last month;
Kellgren-Lawrence grade 2 or above and definite medial tibiofemoral compartment OA on x-ray (grade 1 or higher medial joint space narrowing and joint space narrowing grade medial>lateral);
Presence of at least one bone marrow lesion in the medial knee compartment on MRI;

Exclusion Criteria

History of knee surgery ie joint replacement and tibial osteotomy in either knee and/or planning to undergo knee or hip surgery in the next 3 months;
Other muscular, joint, neurological conditions other than knee OA affecting lower limb function or interfering with daily cane use;
Current and previous (ie previous 3 months) use of canes; Current and previous (ie previous 3 months) irregular use of shoe inserts, knee or ankle braces or customized shoes prescribed by a health professional;
Current and previous treatments (ie previous 6 months) of knee arthroscopy and intra-articular injections in the knee;
Contra-indications for MRI;
Use of potential disease-modifying drugs;

Study & Design

• Study Type: Interventional
• Study Design: Not specified